What effects should we expect these regulations to have on firm size, and (leaving aside the value or harm of the regulation's direct effect) is this change in firm size efficient? You might think about Coase's 1937 paper, The Nature of the Firm.
Bonus question 1: What are some other regulations that have similar effects? (I don't know the answer to this one.)
Bonus question 2: Is there any empirical work that tries to estimate the effect of such regulations on firm size? (I don't know the answer to this one, either).
Bonus question 3 (for econometrics students): Where would you ideally look to test this, and how would you do it? (I think there is a clear "best answer" to this.)
If you have responses, feel free to post them in the comments.